Ethinyl estradiol and norelgestromin transdermal and Lorazepam Intensol
Determining the interaction of Ethinyl estradiol and norelgestromin transdermal and Lorazepam Intensol and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Oral contraceptives may increase the clearance rate of benzodiazepines that undergo glucuronidation (such as lorazepam, oxazepam, and temazepam). Close observation for signs and symptoms of altered benzodiazepine effect is recommended.
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- Billedeau SM, Holder CL, Getek TA "High-performance liquid chromatography of the antihistamine pyrilamine and its N-oxide using electrochemical detection." J Chromatogr 534 (1990): 151-9
- Patwardhan RV, Mitchell MC, Johnson RF, Schenker S "Differential effects of oral contraceptive steroids on the metabolism of benzodiazepines." Hepatology 3 (1983): 248-53
- Abernethy DR, Greenblatt DJ, Divoll M, Arendt R, Ochs HR, Shader RI "Impairment of diazepam metabolism by low-dose estrogen-containing oral-contraceptive steroids." N Engl J Med 306 (1982): 791-2
- Stoehr GP, Kroboth PD, Juhl RP, Wender DB, Phillips JP, Smith RB "Effect of oral contraceptives on triazolam, temazepam, alprazolam, and lorazepam kinetics." Clin Pharmacol Ther 36 (1984): 683-90
Generic Name: ethinyl estradiol / norelgestromin
Brand name: Xulane, Ortho Evra
Synonyms: Ethinyl estradiol and norelgestromin (transdermal), Ethinyl Estradiol and Norelgestromin
Generic Name: lorazepam
Brand name: Ativan, Lorazepam Intensol
Synonyms: Lorazepam Intensol (Oral)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Ethinyl estradiol and norelgestromin transdermal-Lorazepam Oral Concentrate
- Ethinyl estradiol and norelgestromin transdermal-Lorazepam Oral Solution
- Ethinyl estradiol and norelgestromin transdermal-Lorazepam Tablets
- Ethinyl estradiol and norelgestromin transdermal-Lorbrena
- Ethinyl estradiol and norelgestromin transdermal-Lorcaserin
- Ethinyl estradiol and norelgestromin transdermal-Lorcaserin Extended-Release Tablets
- Lorazepam Intensol-Ethinyl estradiol and norethindrone
- Lorazepam Intensol-Ethinyl estradiol and norethindrone birth control
- Lorazepam Intensol-Ethinyl Estradiol and Norethindrone Chewable Tabs & Ferrous Fumarate Tabs
- Lorazepam Intensol-Ethinyl estradiol and norethindrone HRT
- Lorazepam Intensol-Ethinyl Estradiol and Norethindrone Tablets
- Lorazepam Intensol-Ethinyl estradiol and norgestimate