Ethinyl estradiol and norelgestromin transdermal and Tranylcypromine Sulfate

• Generic Name: ethinyl estradiol / norelgestromin
• Dosage Forms: n.a.
• Other Brand Names: Xulane, Ortho Evra

Ethinyl estradiol and norelgestromin contains a combination of female hormones that prevent ovulation (the release of an egg from an ovary). ethinyl estradiol and norelgestromin also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Ethinyl estradiol and norelgestromin transdermal (skin patch) is used as contraception to prevent pregnancy.

Ethinyl estradiol and norelgestromin may also be used for purposes not listed in this medication guide.

• Generic Name: tranylcypromine
• Dosage Forms: n.a.
• Other Brand Names: Parnate

Treatment of major depressive disorder without melancholia.

Efficacy in major depressive disorder with melancholia (endogenous features) not established.

MAO inhibitors appear particularly effective in treatment of major depressive disorder with atypical features, although other antidepressants (e.g., SSRIs) may initially be used because of their more favorable adverse effect profile.

Because of potential for serious adverse effects and necessity of dietary restrictions, MAO inhibitors (e.g., phenelzine, tranylcypromine) generally are not used as initial therapy for major depressive disorder, but are reserved for carefully selected patients who can be closely supervised and who have depression refractory to other antidepressants (e.g., SSRIs, SNRIs, TCAs) or in whom other therapies are contraindicated.