Ethinyl estradiol and norethindrone HRT and Tofranil injection
Determining the interaction of Ethinyl estradiol and norethindrone HRT and Tofranil injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:The bioavailability and serum concentration of tricyclic antidepressants may be increased in women taking oral contraceptives. The mechanism may be related to inhibition of the hepatic metabolism of tricyclics. The clinical significance of this interaction is unknown.
- Edelbroek PM, Zitman FG, Knoppert-van der Klein EA, van Putten PM, de Wolff FA "Therapeutic drug monitoring of amitriptyline: impact of age, smoking and contraceptives on drug and metabolite levels in bulimic women." Clin Chim Acta 165 (1987): 177-87
- Khurana RC "Estrogen-imipramine interaction." JAMA 222 (1972): 702-3
- Somani SM, Khurana RC "Mechanism of estrogen-imipramine interaction." JAMA 223 (1973): 560
- Prange AJ, Wilson IC, Alltop LB "Estrogen may well affect response to antidepressant." JAMA 219 (1972): 143-4
- Abernethy DR, Greenblatt DJ, Shader RI "Imipramine disposition in users of oral contraceptive steroids." Clin Pharmacol Ther 35 (1984): 792-7
Generic Name: ethinyl estradiol / norethindrone
Brand name: femhrt 05 mg/25 mcg, Fyavolv, Jevantique Lo, Jinteli, Blisovi 24 Fe, Estrostep Fe, Femcon Fe, Kaitlib FE, Lo Minastrin Fe, Microgestin 24 Fe, Norinyl 1+35, Ortho-Novum 7/7/7, Taytulla, Tri-Norinyl, Zenchent, Blisovi 24 Fe, Blisovi Fe 15/30, Blisovi Fe 1/20, Gildess 24 Fe, Gildess Fe 15/30, Gildess Fe 1/20, Junel Fe 15/30, Junel Fe 1/20, Junel Fe 24, Larin 24 Fe, Larin Fe 15/30, Larin Fe 1/20, Lo Loestrin Fe, Loestrin 24 Fe, Loestrin Fe 15/30, Loestrin Fe 1/20, Lomedia 24 Fe, Microgestin 24 Fe, Microgestin Fe 15/30, Microgestin Fe 1/20, Tarina Fe 1/20, Tilia Fe, Tri-Legest Fe, Femcon Fe, Generess FE, Loestrin 1/20, Ovcon 35, Brevicon
Synonyms: Ethinyl estradiol and norethindrone (HRT), Ethinyl Estradiol and Norethindrone
Generic Name: imipramine
Brand name: Tofranil, Tofranil-PM
Synonyms: Tofranil
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Ethinyl estradiol and norethindrone HRT-Tofranil-PM
- Ethinyl estradiol and norethindrone HRT-Tol-Tab
- Ethinyl estradiol and norethindrone HRT-Tolazamide
- Ethinyl estradiol and norethindrone HRT-Tolbutamide
- Ethinyl estradiol and norethindrone HRT-Tolcapone
- Ethinyl estradiol and norethindrone HRT-Tolectin 600
- Tofranil injection-Ethinyl Estradiol and Norethindrone Tablets
- Tofranil injection-Ethinyl estradiol and norgestimate
- Tofranil injection-Ethinyl estradiol and norgestrel
- Tofranil injection-Ethinyl estradiol and segesterone vaginal ring
- Tofranil injection-Ethinyl Estradiol, Drospirenone, and Levomefolate
- Tofranil injection-Ethinyl estradiol, folic acid, and levonorgestrel