Ethotoin and Vibramycin Calcium
Determining the interaction of Ethotoin and Vibramycin Calcium and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Before using doxycycline, tell your doctor if you also use ethotoin. You may need a dose adjustment or special tests in order to safely take both medications together. This may decrease the effectiveness of doxycycline. If you take both medications together, tell your doctor if your infection worsens. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Phenytoin (and other hydantoins) may significantly decrease doxycycline half-life resulting in decreased antimicrobial effectiveness. The mechanism may be related to induction of doxycycline metabolism.
MANAGEMENT: Patients should be monitored for altered doxycycline efficacy. It may be necessary to increase doxycycline dosage. Alternative antimicrobial therapy with a different tetracycline or a different class of antimicrobial agent may be preferable.
- Neuvonen PJ, Penttila O, Lehtovaara R, Aho K "Effect of antiepileptic drugs on the elimination of various tetracycline derivatives." Eur J Clin Pharmacol 9 (1975): 147-54
- Penttila O, Neuvonen PJ, Aho K, Lehtovaara R "Interaction between doxycycline and some antiepileptic drugs." Br Med J 2 (1974): 470-2
Generic Name: doxycycline
Brand name: Vibramycin, Acticlate, Adox Pak 2/100, Adoxa, Adoxa Pak 1/100, Adoxa Pak 1/150, Avidoxy, Monodox, Morgidox, Oraxyl, TargaDOX, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Mondoxyne NL, Oracea, Periostat Targadox, Vibramycin Calcium, Vibramycin Hyclate, Vibramycin monohydrate, Vibra-Tabs, Doxy 100, TargaDOX
Synonyms: Vibramycin (Suspension), Vibramycin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Ethotoin-Vibramycin Hyclate
- Ethotoin-Vicks 44 Cold, Flu and Cough
- Ethotoin-Vicks 44 Cough Relief
- Ethotoin-Vicks DayQuil Multi-Symptom
- Ethotoin-Vicks DayQuil Multi-Symptom Cold/Flu Relief
- Ethotoin-Vicks DayQuil Severe Cold/Flu
- Vibramycin Calcium-Ethynodiol diacetate and Ethinyl Estradiol
- Vibramycin Calcium-Ethyol
- Vibramycin Calcium-Etidronate
- Vibramycin Calcium-Etidronate Disodium
- Vibramycin Calcium-Etidronate Oral, Intravenous
- Vibramycin Calcium-Etodolac