Etravirine and Zovia 1/35

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Coadministration with etravirine may slightly increase the plasma concentrations of ethinyl estradiol. The mechanism of interaction has not been described. In 16 study subjects administered ethinyl estradiol-norethindrone (35 mcg-1 mg) once a day with etravirine, ethinyl estradiol peak plasma concentration (Cmax), systemic exposure (AUC) and trough plasma concentration (Cmin) increased by 33%, 22% and 9%, respectively. These changes were statistically, but not clinically, significant. Etravirine had no effect on the pharmacokinetics of norethindrone. Etravirine and ethinyl estradiol-norethindrone may be coadministered without any dosage adjustments. No data are available for other estrogen or progestin products.

Etravirine

Generic Name: etravirine

Brand name: Intelence

Synonyms: n.a.

What is Etravirine?

Zovia 1/35

Generic Name: ethinyl estradiol / ethynodiol

Brand name: Kelnor, Zovia 1/35, Zovia 1/50, Demulen 1/35, Demulen 1/50, Zovia 1/35e, Kelnor 1/50, Kelnor 1/35, Zovia 1/50e

Synonyms: Zovia 1/35E

What is Zovia 1/35?