Excedrin Mild Headache and Up and Up Acid Reducer
Determining the interaction of Excedrin Mild Headache and Up and Up Acid Reducer and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Animal studies have suggested that ranitidine may potentiate the hepatotoxicity of acetaminophen, however, a double-blind placebo-controlled crossover study has failed to confirm this finding in humans. Acetaminophen dosage adjustments are not indicated.
- Rogers SA, Gale KC, Newton JF, et al "Inhibition by ranitidine of acetaminophen conjugation and its possible role in ranitidine potentiation of acetaminophen-induced hepatotoxicity." J Pharmacol Exp Ther 245 (1988): 887-94
- Jack D, Thomas M, Skidmore IF "Ranitidine and paracetamol metabolism." Lancet 2 (1985): 1067
Generic Name: acetaminophen / caffeine
Brand name: Excedrin Mild Headache, Excedrin Quick Tab Peppermint, Excedrin Quick Tab Spearmint, Excedrin Tension Headache, Excedrin Tension Headache Caplet, Excedrin Tension Headache Express Gels, Excedrin Tension Headache Geltab, Valorin Extra, Excedrin Tension Headache Express
Synonyms: n.a.
Generic Name: ranitidine
Brand name: Zantac
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Excedrin Mild Headache-Up and Up All Day Allergy Relief
- Excedrin Mild Headache-Up and Up All Day Allergy Relief D
- Excedrin Mild Headache-Up and Up Anti-Diarrheal Solution
- Excedrin Mild Headache-Up and Up Childrens All Day Allergy Relief
- Excedrin Mild Headache-Up and Up Migraine Relief
- Excedrin Mild Headache-Up and Up Minoxidil
- Up and Up Acid Reducer-Excedrin PM
- Up and Up Acid Reducer-Excedrin Quick Tab Peppermint
- Up and Up Acid Reducer-Excedrin Quick Tab Spearmint
- Up and Up Acid Reducer-Excedrin Sinus Headache Caplet
- Up and Up Acid Reducer-Excedrin Tension Headache
- Up and Up Acid Reducer-Excedrin Tension Headache Caplet