Excedrin PM and Ranitidine Tablets and Capsules
Determining the interaction of Excedrin PM and Ranitidine Tablets and Capsules and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Animal studies have suggested that ranitidine may potentiate the hepatotoxicity of acetaminophen, however, a double-blind placebo-controlled crossover study has failed to confirm this finding in humans. Acetaminophen dosage adjustments are not indicated.
- Rogers SA, Gale KC, Newton JF, et al "Inhibition by ranitidine of acetaminophen conjugation and its possible role in ranitidine potentiation of acetaminophen-induced hepatotoxicity." J Pharmacol Exp Ther 245 (1988): 887-94
- Jack D, Thomas M, Skidmore IF "Ranitidine and paracetamol metabolism." Lancet 2 (1985): 1067
Generic Name: acetaminophen / diphenhydramine
Brand name: Aceta-Gesic, Coricidin Night Time Cold Relief, Excedrin PM, Headache Relief PM, Legatrin PM, Mapap PM, Midol PM, Night Time Pain, Pain Relief PM Extra Strength, Percogesic Extra Strength, Tylenol Cold Relief Nighttime, Tylenol PM, Tylenol Sore Throat Nighttime, Unisom with Pain Relief, Tylenol Extra Strength PM, Bayer Select Max Strength Night Time Pain, Genapap PM, Excedrin PM Caplet, Sominex Pain Relief Formula, Tylenol Severe Allergy Caplet, Anacin PM. Aspirin Free, Tylenol Extra Strength PM Vanilla, Tylenol Cold Relief Caplet, Tylenol Cold Relief Nighttime Caplet, Tylenol Extra Strength PM Rapid Release Gelcaps, Excedrin PM Express, Percogesic Original Strength, Tylenol Cold Relief, Tylenol Severe Allergy
Synonyms: n.a.
Generic Name: ranitidine
Brand name: Zantac
Synonyms: Ranitidine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Excedrin PM-Ranolazine
- Excedrin PM-Ranolazine ER Tablets
- Excedrin PM-Rapaflo
- Excedrin PM-Rapamune
- Excedrin PM-Rapamune (Sirolimus Oral Solution)
- Excedrin PM-Rapamune (Sirolimus Tablets)
- Ranitidine Tablets and Capsules-Excedrin Quick Tab Peppermint
- Ranitidine Tablets and Capsules-Excedrin Quick Tab Spearmint
- Ranitidine Tablets and Capsules-Excedrin Sinus Headache Caplet
- Ranitidine Tablets and Capsules-Excedrin Tension Headache
- Ranitidine Tablets and Capsules-Excedrin Tension Headache Caplet
- Ranitidine Tablets and Capsules-Excedrin Tension Headache Express Gels