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Exelon Transdermal and Nicotine Oral, Transdermal

Determining the interaction of Exelon Transdermal and Nicotine Oral, Transdermal and the possibility of their joint administration.

Check result:
Exelon Transdermal <> Nicotine Oral, Transdermal
Relevance: 25.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

The manufacturer has reported that nicotine use increases the oral clearance of rivastigmine by 23%. The mechanism of this interaction has not been reported. Because the dose of rivastigmine is individually titrated to tolerability, no specific rivastigmine dosage adjustments are recommended.

References
  • "Product Information. Exelon (rivastigmine)" Novartis Pharmaceuticals, East Hanover, NJ.
Exelon Transdermal

Generic Name: rivastigmine

Brand name: Exelon

Synonyms: Exelon

Nicotine Oral, Transdermal

Generic Name: nicotine

Brand name: Leader Nicotine Polacrilex, Nicorelief, Nicorette, Thrive, Commit, Habitrol, Nicoderm C-Q, Nicotine System Kit, Nicoderm CQ, Nicotrol Inhaler, Nicotrol NS

Synonyms: Nicotine Gum and Lozenges, Nicotine

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle