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Exforge HCT and Zyflo CR

Determining the interaction of Exforge HCT and Zyflo CR and the possibility of their joint administration.

Check result:
Exforge HCT <> Zyflo CR
Relevance: 15.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

The antihypertensive effect of amlodipine and thiazide diuretics may be additive. Management consists of monitoring blood pressure during coadministration, especially during the first 1 to 3 weeks of therapy.

References
  • Kaplan NM "Amlodipine in the treatment of hypertension." Postgrad Med J 67 Suppl 5 (1991): s15-9
Exforge HCT

Generic Name: amlodipine / hydrochlorothiazide / valsartan

Brand name: Exforge HCT

Synonyms: n.a.

Zyflo CR

Generic Name: zileuton

Brand name: Zyflo, Zyflo CR

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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Disease interaction