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EZChar and Ipecac syrup

Determining the interaction of EZChar and Ipecac syrup and the possibility of their joint administration.

Check result:
EZChar <> Ipecac syrup
Relevance: 13.06.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using charcoal together with ipecac. Using these medications together can make ipecac less effective. Do not take charcoal with any other medication. Charcoal binds to other drugs and reduces their effectiveness, which could become dangerous. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Administration of activated charcoal with ipecac may decrease the effectiveness of the ipecac. The alkaloids of ipecac may be adsorbed onto the charcoal. The concomitant use of ipecac and charcoal does not appear to improve patient outcome over charcoal alone.

MANAGEMENT: Ipecac and activated charcoal are generally not administered together routinely; although the prior administration of one agent should not be considered a contraindication to the administration of the other agent if it is deemed necessary by the attending physician. If both agents are used to treat a patient, the ipecac is generally given first and the charcoal is given after vomiting has stopped.

References
  • Bond GR "The role of activated charcoal and gastric emptying in gastrointestinal decontamination: A state-of-the-art review." Ann Emerg Med 39 (2002): 273-86
  • Krenzelok EP, McGuigan M, Lheur P "Position statement: ipecac syrup. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinica Toxicologists." J Toxicol Clin Toxicol 35 (1997): 699-709
  • Chyka PA, Seger D "Position statement: single-dose activated charcoal. American Academy of Clinical Toxicology; European Association of Poisons Centres an Clinical Toxicologists." J Toxicol Clin Toxicol 35 (1997): 721-41
  • Covington TR, Lawson LC, Young LL, eds. "Handbook of Nonprescription Drugs. 10th ed." Washington, DC: American Pharmaceutical Association (1993):
EZChar

Generic Name: charcoal

Brand name: Actidose-Aqua, Activated Charcoal, Charcoal Plus DS, EZChar, Insta-Char, Liqui-Char, Optimum Charcoal, Liqui-Char with Sorbitol, Charcocaps, Activated Charcoal with Sorbitol, Charcoaid 2000, Charcoaid-G, Char-Flo with Sorbitol, Charcoaid, Charcodote, Char-Flo Aqueous Base, Actidose-Aqua Advance, JL. Bragg's Medicinal Charcoal, Medicoal, Karbons, Carbomix, Carbosorb X, Charcotabs, Healthstream Activated Charcoal, Charcotrace, Chem Mart Nasal Decongestant Capsule, Pharmacia Carbosorb, Norit, Eucarbon, Active Carbon

Synonyms: n.a.

Ipecac syrup

Generic Name: ipecac

Brand name:

Synonyms: Ipecac syrup (Oral)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction