About us Contacts Drug interactions: 390 212
Drug search by name

Ezogabine and Thiopental

Determining the interaction of Ezogabine and Thiopental and the possibility of their joint administration.

Check result:
Ezogabine <> Thiopental
Relevance: 09.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Before you undergo surgery where anesthesia with thiopental may be given, let your doctor know if you are currently being treated with ezogabine. In studies with rats, ezogabine has been shown to prolong the sleep time induced by thiopental. Studies have not been performed in human. You may need to be monitored more closely during anesthesia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Ezogabine may increase the duration of some anesthetics. In studies with rats, thiopental-induced sleep time was increased from 4 minutes to 53 minutes and propofol-induced sleep time increased from 8 minutes to 12 minutes. Human clinical data are lacking.

MANAGEMENT: It may be advisable to monitor anesthetized patients for excessive sleep duration if they have been treated with ezogabine.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Ezogabine

Generic Name: ezogabine

Brand name: Potiga

Synonyms: n.a.

Thiopental

Generic Name: thiopental

Brand name:

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction