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Factive and Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)

Determining the interaction of Factive and Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets) and the possibility of their joint administration.

Check result:

Factive <> Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)

Relevance: 19.01.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration with omeprazole has been shown to slightly increase the plasma concentrations of gemifloxacin. According to the product labeling, omeprazole (40 mg once a day for 4 days) increased the peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) of gemifloxacin (320 mg single dose) by an average of 11% and 10%, respectively. These increases are not considered clinically significant.

References

"Product Information. Factive (gemifloxacin)." GeneSoft Inc, San Francisco, CA.

Factive

Generic Name: gemifloxacin

Brand name: Factive

Synonyms: n.a.

What is Factive?

Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)

Generic Name: omeprazole / sodium bicarbonate

Brand name: Zegerid, Zegerid OTC

Synonyms: Zegerid

What is Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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