Famotidine and ibuprofen and Nicotine Transdermal System
Determining the interaction of Famotidine and ibuprofen and Nicotine Transdermal System and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:H2 antagonists may alter the disposition of nonsteroidal anti-inflammatory drugs (NSAIDs), resulting in increased or decreased plasma concentrations. Data are varied, even for the same NSAID. The mechanism may be related to inhibition of metabolism, changes in gastric pH that decrease absorption, and/or reduced urinary elimination. Statistically significant changes have been small and of limited clinical significance. Clinical monitoring of patient response and tolerance is recommended.
- Scavone JM, Greenblatt DJ, Matlis R, Harmatz JS "Interaction of oxaprozin with acetaminophen, cimetidine, and ranitidine." Eur J Clin Pharmacol 31 (1986): 371-4
- Said SA, Foda AM "Influence of cimetidine on the pharmacokinetics of piroxicam in rat and man." Arzneimittelforschung 39 (1989): 790-2
- "Product Information. Daypro (oxaprozin)." Searle, Skokie, IL.
Generic Name: famotidine / ibuprofen
Brand name: Duexis
Synonyms: Ibuprofen and Famotidine
Generic Name: nicotine
Brand name: Leader Nicotine Polacrilex, Nicorelief, Nicorette, Thrive, Commit, Habitrol, Nicoderm C-Q, Nicotine System Kit, Nicoderm CQ, Nicotrol Inhaler, Nicotrol NS
Synonyms: Nicotine Gum and Lozenges, Nicotine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Famotidine and ibuprofen-Nicotine Transdermal System Step 1
- Famotidine and ibuprofen-Nicotine Transdermal System Step 2
- Famotidine and ibuprofen-Nicotine Transdermal System Step 3
- Famotidine and ibuprofen-Nicotinex
- Famotidine and ibuprofen-Nicotrol
- Famotidine and ibuprofen-Nicotrol Inhalant
- Nicotine Transdermal System-Famotidine Chewable Tablets
- Nicotine Transdermal System-Famotidine Injection
- Nicotine Transdermal System-Famotidine Injection Solution
- Nicotine Transdermal System-Famotidine Oral Suspension
- Nicotine Transdermal System-Famotidine Tablets
- Nicotine Transdermal System-Famotidine, Calcium Carbonate, and Magnesium Hydroxide