Fedratinib and Omeprazole Delayed-Release Capsules and Tablets (OTC)
Determining the interaction of Fedratinib and Omeprazole Delayed-Release Capsules and Tablets (OTC) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.MONITOR: Coadministration with CYP450 2C19 inhibitors may increase the plasma concentrations of fedratinib, which is a substrate of the isoenzyme. However, clinical data evaluating the interaction are not available. MANAGEMENT: Caution is recommended with the concomitant use of fedratinib and CYP450 2C19 inhibitors. Patients should be monitored for adverse effects including anemia, thrombocytopenia, diarrhea, nausea, vomiting, and liver (ALT, AST) and pancreatic (amylase, lipase) enzyme elevations. References "Product Information. Inrebic (fedratinib)." Celgene Corporation, Summit, NJ.
Professional:MONITOR: Coadministration with CYP450 2C19 inhibitors may increase the plasma concentrations of fedratinib, which is a substrate of the isoenzyme. However, clinical data evaluating the interaction are not available.
MANAGEMENT: Caution is recommended with the concomitant use of fedratinib and CYP450 2C19 inhibitors. Patients should be monitored for adverse effects including anemia, thrombocytopenia, diarrhea, nausea, vomiting, and liver (ALT, AST) and pancreatic (amylase, lipase) enzyme elevations.
- "Product Information. Inrebic (fedratinib)." Celgene Corporation, Summit, NJ.
Generic Name: omeprazole
Brand name: FIRST Omeprazole, Omeprazole + SyrSpend SF Alka, Prilosec, Prilosec OTC, Zegerid>, Prilosec, Prilosec OTC
Synonyms: Omeprazole
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Fedratinib-Omeprazole Orally-Disintegrating Tablets
- Fedratinib-Omeprazole Powder for Oral Suspension
- Fedratinib-Omeprazole Tablets
- Fedratinib-Omeprazole, Clarithromycin, and Amoxicillin
- Fedratinib-Omidria
- Fedratinib-Omidria Ophthalmic
- Omeprazole Delayed-Release Capsules and Tablets (OTC)-Fedratinib Hydrochloride
- Omeprazole Delayed-Release Capsules and Tablets (OTC)-Feiba
- Omeprazole Delayed-Release Capsules and Tablets (OTC)-Feiba NF
- Omeprazole Delayed-Release Capsules and Tablets (OTC)-Feiba VH Immuno
- Omeprazole Delayed-Release Capsules and Tablets (OTC)-Feiba-VH
- Omeprazole Delayed-Release Capsules and Tablets (OTC)-Felbamate