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Fedratinib Hydrochloride and Kybella

Determining the interaction of Fedratinib Hydrochloride and Kybella and the possibility of their joint administration.

Check result:
Fedratinib Hydrochloride <> Kybella
Relevance: 24.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this interaction is not currently available.MONITOR: Coadministration with agents that alter hemostasis such as anticoagulants, platelet inhibitors, thrombin inhibitors, thrombolytics, or agents that commonly cause thrombocytopenia may increase the risk of submental hematoma or bruising in association with deoxycholic acid administration. In clinical trials, 72% of subjects treated with deoxycholic acid experienced injection site hematoma or bruising. MANAGEMENT: Deoxycholic acid should be used with caution in patients receiving drugs that may interfere with hemostasis. References "Product Information. Kybella (deoxycholic acid)." Kythera Biopharmaceuticals, Inc., Westlake Village, CA.

Professional:

MONITOR: Coadministration with agents that alter hemostasis such as anticoagulants, platelet inhibitors, thrombin inhibitors, thrombolytics, or agents that commonly cause thrombocytopenia may increase the risk of submental hematoma or bruising in association with deoxycholic acid administration. In clinical trials, 72% of subjects treated with deoxycholic acid experienced injection site hematoma or bruising.

MANAGEMENT: Deoxycholic acid should be used with caution in patients receiving drugs that may interfere with hemostasis.

References
  • "Product Information. Kybella (deoxycholic acid)." Kythera Biopharmaceuticals, Inc., Westlake Village, CA.
Fedratinib Hydrochloride

Generic Name: fedratinib

Brand name: Inrebic

Synonyms: Fedratinib

Kybella

Generic Name: deoxycholic acid

Brand name: Kybella

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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