Fedratinib Hydrochloride and Phenytoin Chewable Tablets
Determining the interaction of Fedratinib Hydrochloride and Phenytoin Chewable Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.GENERALLY AVOID: Coadministration with potent or moderate inducers of CYP450 3A4 may decrease the plasma concentrations of fedratinib, which is a substrate of the isoenzyme. However, clinical data evaluating this interaction are not available. MANAGEMENT: According to the product labeling, concomitant use of fedratinib with potent or moderate CYP450 3A4 inducers should be avoided. References "Product Information. Inrebic (fedratinib)." Celgene Corporation, Summit, NJ.
Professional:GENERALLY AVOID: Coadministration with potent or moderate inducers of CYP450 3A4 may decrease the plasma concentrations of fedratinib, which is a substrate of the isoenzyme. However, clinical data evaluating this interaction are not available.
MANAGEMENT: According to the product labeling, concomitant use of fedratinib with potent or moderate CYP450 3A4 inducers should be avoided.
- "Product Information. Inrebic (fedratinib)." Celgene Corporation, Summit, NJ.
Generic Name: fedratinib
Brand name: Inrebic
Synonyms: Fedratinib
Generic Name: phenytoin
Brand name: Dilantin, Phenytek, Dilantin Infatabs, Phenytoin Sodium, Prompt
Synonyms: Phenytoin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Fedratinib Hydrochloride-Phenytoin Extended-Release Capsules
- Fedratinib Hydrochloride-Phenytoin Infatabs
- Fedratinib Hydrochloride-Phenytoin injection
- Fedratinib Hydrochloride-Phenytoin Intravenous
- Fedratinib Hydrochloride-Phenytoin Oral Suspension
- Fedratinib Hydrochloride-Phenytoin Sodium
- Phenytoin Chewable Tablets-Feiba
- Phenytoin Chewable Tablets-Feiba NF
- Phenytoin Chewable Tablets-Feiba VH Immuno
- Phenytoin Chewable Tablets-Feiba-VH
- Phenytoin Chewable Tablets-Felbamate
- Phenytoin Chewable Tablets-Felbamate Oral Suspension