Fedratinib Hydrochloride and Phenytoin Sodium, Prompt injection
Determining the interaction of Fedratinib Hydrochloride and Phenytoin Sodium, Prompt injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.GENERALLY AVOID: Coadministration with potent or moderate inducers of CYP450 3A4 may decrease the plasma concentrations of fedratinib, which is a substrate of the isoenzyme. However, clinical data evaluating this interaction are not available. MANAGEMENT: According to the product labeling, concomitant use of fedratinib with potent or moderate CYP450 3A4 inducers should be avoided. References "Product Information. Inrebic (fedratinib)." Celgene Corporation, Summit, NJ.
Professional:GENERALLY AVOID: Coadministration with potent or moderate inducers of CYP450 3A4 may decrease the plasma concentrations of fedratinib, which is a substrate of the isoenzyme. However, clinical data evaluating this interaction are not available.
MANAGEMENT: According to the product labeling, concomitant use of fedratinib with potent or moderate CYP450 3A4 inducers should be avoided.
- "Product Information. Inrebic (fedratinib)." Celgene Corporation, Summit, NJ.
Generic Name: fedratinib
Brand name: Inrebic
Synonyms: Fedratinib
Generic Name: phenytoin
Brand name: Dilantin, Phenytoin Sodium, Prompt, Phenytek, Dilantin Infatabs
Synonyms: Phenytoin Sodium, Prompt (injection)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Fedratinib Hydrochloride-Phenytoin Suspension
- Fedratinib Hydrochloride-Philith
- Fedratinib Hydrochloride-Phillips Milk of Magnesia
- Fedratinib Hydrochloride-Phisohex
- Fedratinib Hydrochloride-Phl-Fluoxetine
- Fedratinib Hydrochloride-Phlemex
- Phenytoin Sodium, Prompt injection-Feiba
- Phenytoin Sodium, Prompt injection-Feiba NF
- Phenytoin Sodium, Prompt injection-Feiba VH Immuno
- Phenytoin Sodium, Prompt injection-Feiba-VH
- Phenytoin Sodium, Prompt injection-Felbamate
- Phenytoin Sodium, Prompt injection-Felbamate Oral Suspension