Fedratinib Hydrochloride and Pms-Isoniazid
Determining the interaction of Fedratinib Hydrochloride and Pms-Isoniazid and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.GENERALLY AVOID: Coadministration with dual CYP450 3A4 and 2C19 inhibitors may increase the plasma concentrations of fedratinib, which is a substrate of these isoenzymes. However, clinical data evaluating the interaction are not available. MANAGEMENT: According to the product labeling, concomitant use of fedratinib with dual CYP450 3A4 and 2C19 inhibitors should be avoided. References "Product Information. Inrebic (fedratinib)." Celgene Corporation, Summit, NJ.
Professional:GENERALLY AVOID: Coadministration with dual CYP450 3A4 and 2C19 inhibitors may increase the plasma concentrations of fedratinib, which is a substrate of these isoenzymes. However, clinical data evaluating the interaction are not available.
MANAGEMENT: According to the product labeling, concomitant use of fedratinib with dual CYP450 3A4 and 2C19 inhibitors should be avoided.
- "Product Information. Inrebic (fedratinib)." Celgene Corporation, Summit, NJ.
Generic Name: fedratinib
Brand name: Inrebic
Synonyms: Fedratinib
Generic Name: isoniazid
Brand name: Nydrazid
Synonyms: Isoniazid
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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