Fedratinib Hydrochloride and Siltuximab

• Generic Name: fedratinib
• Dosage Forms: n.a.
• Other Brand Names: Inrebic

Fedratinib hydrochloride is a kinase inhibitor indicated for the treatment of adult patients with intermediate-2 or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis (MF).

• Generic Name: siltuximab
• Dosage Forms: n.a.
• Other Brand Names: Sylvant

Siltuximab is used to treat Multicentric Castleman's Disease (MCD). MCD is a rare condition in which the body produces too much of a certain type of white blood cell. MCD can increase your risk of certain cancers by changing the way your immune system works.

Siltuximab is not for use in people who have human immunodeficiency virus (HIV) or human herpesvirus-8.

Siltuximab may also be used for purposes not listed in this medication guide.