Fedratinib Hydrochloride and Sustiva (Efavirenz Tablets)
Determining the interaction of Fedratinib Hydrochloride and Sustiva (Efavirenz Tablets) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.GENERALLY AVOID: Coadministration with potent or moderate inducers of CYP450 3A4 may decrease the plasma concentrations of fedratinib, which is a substrate of the isoenzyme. However, clinical data evaluating this interaction are not available. MANAGEMENT: According to the product labeling, concomitant use of fedratinib with potent or moderate CYP450 3A4 inducers should be avoided. References "Product Information. Inrebic (fedratinib)." Celgene Corporation, Summit, NJ.
Professional:GENERALLY AVOID: Coadministration with potent or moderate inducers of CYP450 3A4 may decrease the plasma concentrations of fedratinib, which is a substrate of the isoenzyme. However, clinical data evaluating this interaction are not available.
MANAGEMENT: According to the product labeling, concomitant use of fedratinib with potent or moderate CYP450 3A4 inducers should be avoided.
- "Product Information. Inrebic (fedratinib)." Celgene Corporation, Summit, NJ.
Generic Name: fedratinib
Brand name: Inrebic
Synonyms: Fedratinib
Generic Name: efavirenz
Brand name: Sustiva
Synonyms: Sustiva
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Fedratinib Hydrochloride-Sustol
- Fedratinib Hydrochloride-Sustol injection
- Fedratinib Hydrochloride-SuTan
- Fedratinib Hydrochloride-SuTan-DM
- Fedratinib Hydrochloride-Sutent
- Fedratinib Hydrochloride-Suvorexant
- Sustiva (Efavirenz Tablets)-Feiba
- Sustiva (Efavirenz Tablets)-Feiba NF
- Sustiva (Efavirenz Tablets)-Feiba VH Immuno
- Sustiva (Efavirenz Tablets)-Feiba-VH
- Sustiva (Efavirenz Tablets)-Felbamate
- Sustiva (Efavirenz Tablets)-Felbamate Oral Suspension