Fedratinib Hydrochloride and Vitabee 6

• Generic Name: fedratinib
• Dosage Forms: n.a.
• Other Brand Names: Inrebic

Fedratinib hydrochloride is a kinase inhibitor indicated for the treatment of adult patients with intermediate-2 or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis (MF).

• Generic Name: pyridoxine
• Dosage Forms: n.a.
• Other Brand Names: Vitamin B6, Vitelle Nestrex, Pyridoxal 5'-Phosphate

Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are usually available in the foods that you eat. Pyridoxine (vitamin B 6) is necessary for normal breakdown of proteins, carbohydrates, and fats.

Some conditions may increase your need for pyridoxine. These include:

• Alcoholism
• Burns
• Diarrhea
• Dialysis
• Heart disease
• Intestinal problems
• Liver disease
• Overactive thyroid
• Stress, long-term illness, or serious injury
• Surgical removal of stomach

In addition, infants receiving unfortified formulas such as evaporated milk may need additional pyridoxine.

Increased need for pyridoxine should be determined by your health care professional.

Lack of pyridoxine may lead to anemia (weak blood), nerve damage, seizures, skin problems, and sores in the mouth. Your doctor may treat these problems by prescribing pyridoxine for you.

Claims that pyridoxine is effective for treatment of acne and other skin problems, alcohol intoxication, asthma, hemorrhoids, kidney stones, mental problems, migraine headaches, morning sickness, and menstrual problems, or to stimulate appetite or milk production have not been proven.

Injectable pyridoxine is given by or under the supervision of a health care professional. Other forms of pyridoxine are available without a prescription.