Fedratinib Hydrochloride and Vorapaxar
Determining the interaction of Fedratinib Hydrochloride and Vorapaxar and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.MONITOR CLOSELY: Concomitant use of vorapaxar with other agents that affect hemostasis such as anticoagulants, platelet inhibitors, thrombin inhibitors, thrombolytic agents, dextran, nonsteroidal anti-inflammatory agents (chronic), or agents that commonly cause thrombocytopenia may increase the risk of bleeding. MANAGEMENT: Caution is advised if vorapaxar is used in combination with other drugs that affect hemostasis. Close clinical and laboratory observation for hemorrhagic complications is recommended. Patients should be advised to promptly report any signs of bleeding to their doctor, including pain, swelling, headache, dizziness, weakness, prolonged bleeding from cuts, increased menstrual flow, vaginal bleeding, nosebleeds, bleeding of gums from brushing, unusual bleeding or bruising, red or brown urine, or red or black stools. References "Product Information. Zontivity (vorapaxar)." Merck & Company Inc, Whitehouse Station, NJ.
Professional:MONITOR CLOSELY: Concomitant use of vorapaxar with other agents that affect hemostasis such as anticoagulants, platelet inhibitors, thrombin inhibitors, thrombolytic agents, dextran, nonsteroidal anti-inflammatory agents (chronic), or agents that commonly cause thrombocytopenia may increase the risk of bleeding.
MANAGEMENT: Caution is advised if vorapaxar is used in combination with other drugs that affect hemostasis. Close clinical and laboratory observation for hemorrhagic complications is recommended. Patients should be advised to promptly report any signs of bleeding to their doctor, including pain, swelling, headache, dizziness, weakness, prolonged bleeding from cuts, increased menstrual flow, vaginal bleeding, nosebleeds, bleeding of gums from brushing, unusual bleeding or bruising, red or brown urine, or red or black stools.
- "Product Information. Zontivity (vorapaxar)." Merck & Company Inc, Whitehouse Station, NJ.
Generic Name: fedratinib
Brand name: Inrebic
Synonyms: Fedratinib
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Fedratinib Hydrochloride-Vorapaxar Sulfate
- Fedratinib Hydrochloride-Voraxaze
- Fedratinib Hydrochloride-Voriconazole
- Fedratinib Hydrochloride-Voriconazole Injection
- Fedratinib Hydrochloride-Voriconazole Oral, Intravenous
- Fedratinib Hydrochloride-Voriconazole oral/injection
- Vorapaxar-Feiba
- Vorapaxar-Feiba NF
- Vorapaxar-Feiba VH Immuno
- Vorapaxar-Feiba-VH
- Vorapaxar-Felbamate
- Vorapaxar-Felbamate Oral Suspension