Felimazole and Versacloz

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Ask your doctor before using cloZAPine together with methIMAzole. This can increase the effects of cloZAPine. This can cause tiredness, weakness, sore throat, fever, or flu-like symptoms. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Case reports have suggested that concomitant use of clozapine and methimazole may result in acute granulocytopenia. The mechanism of this interaction is unknown but may be related to synergistic effects as both drugs have been associated with agranulocytosis.

MANAGEMENT: If these drugs must be used together, close observation and testing for evidence of granulocytopenia is recommended. Patients should be advised to promptly report any symptoms such as tiredness, weakness, sore throat, fever, stomatitis, malaise, or flu-like symptoms.

Felimazole

Generic Name: methimazole

Brand name: Tapazole, Northyx

Synonyms: Methimazole

What is Felimazole?

Versacloz

Generic Name: clozapine

Brand name: Clozaril, Fazaclo, Versacloz, Clopine, CloZAPine Synthon, Denzapine, Zaponex

Synonyms: n.a.

What is Versacloz?