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Fenofibric acid and Welchol (Colesevelam Oral Suspension)

Determining the interaction of Fenofibric acid and Welchol (Colesevelam Oral Suspension) and the possibility of their joint administration.

Check result:
Fenofibric acid <> Welchol (Colesevelam Oral Suspension)
Relevance: 21.08.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Colesevelam may interfere with the absorption of fenofibric acid when these medications are taken at the same time. This may reduce the blood levels and effects of fenofibric acid. To prevent or minimize the interaction, fenofibric acid should be taken at least 1 hour before or 4 to 6 hours after the colesevelam dose. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Theoretically, bile acid sequestrants may bind to and decrease the gastrointestinal absorption of fenofibrate/fenofibric acid.

MANAGEMENT: Fenofibrate/fenofibric acid should be taken at least 1 hour before or 4 to 6 hours after the bile acid sequestrant.

References
  • "Product Information. Trilipix (fenofibric acid)." Abbott Pharmaceutical, Abbott Park, IL.
  • Canadian Pharmacists Association "e-CPS. Available from: URL: http://www.pharmacists.ca/function/Subscriptions/ecps.cfm?link=eCPS_quikLink."
  • "Product Information. Tricor (fenofibrate)." Abbott Pharmaceutical, Abbott Park, IL.
Fenofibric acid

Generic Name: fenofibric acid

Brand name: Fibricor, Trilipix

Synonyms: Fenofibric Acid

Welchol (Colesevelam Oral Suspension)

Generic Name: colesevelam

Brand name: Welchol, Colesevelam Hydrochloride

Synonyms: Welchol

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.