Fenoldopam and Robitussin Peak Cold Nasal Relief (Acetaminophen and Phenylephrine Tablets)
Determining the interaction of Fenoldopam and Robitussin Peak Cold Nasal Relief (Acetaminophen and Phenylephrine Tablets) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:The use of acetaminophen has been associated with a 32% increase in orally-administered fenoldopam plasma concentrations and a 50% increase in the area under the plasma concentration versus time curve for fenoldopam. These data suggest that acetaminophen may significantly increase exposure to fenoldopam and increase its hypotensive effect. Data are available for orally administered fenoldopam only. Since fenoldopam is available as an intravenously administered drug for emergent hypertension, its dose can be rapidly titrated in cases of hypotension.
- Ziemniak JA, Allison N, Boppana VK, Dubb J, Stote R "The effect of acetaminophen on the disposition of fenoldopam: competition for sulfation." Clin Pharmacol Ther 41 (1987): 275-81
- Brogden RN, Markham A "Fenoldopam: a review of its pharmacodynamic and pharmacokinetic properties and intravenous clinical potential in the management of hypertensive urgencies and emergencies." Drugs 54 (1997): 634-50
Generic Name: acetaminophen / phenylephrine
Brand name: Alka-Seltzer Plus Cold and Sinus, Contac Cold+Flu Non-Drowsy, Excedrin Sinus Headache Caplet, Mapap Sinus Congestion and Pain, QlearQuil Daytime Sinus & Congestion, Robitussin Nasal Relief, Sinus Congestion and Pain Daytime Cool Ice, Sinus Pain & Pressure, Sudafed PE Sinus Headache, Theraflu Daytime Severe Cold, Tylenol Sinus Congestion and Pain, Congespirin Aspirin Free, Neo Citran Extra Strength Cold and Sinus, Mapap Sinus PE, Tylenol Sinus Congestion Daytime, Excedrin Sinus Headache, Non-Pseudo Sinus Pain & Pressure, Robitussin Peak Cold Nasal Relief, Sudafed PE Pressure Plus Pain, Contact Cold and Flu Day, Tylenol Sinus + Headache Day, Vicks Sinex Daytime, Mygrex, Acetaminophen Congestion and Pain, QlearQuil Sinus & Congestion, Vicks DayQuil Sinex
Synonyms: Robitussin Nasal Relief
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Fenoldopam-Robitussin Peak Cold Nasal Relief (Acetaminophen, Chlorpheniramine, and Phenylephrine Tablets)
- Fenoldopam-Robitussin Peak Cold Nighttime Cold + Flu
- Fenoldopam-Robitussin Pediatric Cough & Cold Long-Acting
- Fenoldopam-Robitussin Severe Congestion
- Fenoldopam-Rocaltrol (Calcitriol Capsules)
- Fenoldopam-Rocaltrol (Calcitriol Oral Solution)
- Robitussin Peak Cold Nasal Relief (Acetaminophen and Phenylephrine Tablets)-Fenoldopam Intravenous
- Robitussin Peak Cold Nasal Relief (Acetaminophen and Phenylephrine Tablets)-Fenoprofen
- Robitussin Peak Cold Nasal Relief (Acetaminophen and Phenylephrine Tablets)-Fenoprofen Calcium
- Robitussin Peak Cold Nasal Relief (Acetaminophen and Phenylephrine Tablets)-Fenoprofen Capsules
- Robitussin Peak Cold Nasal Relief (Acetaminophen and Phenylephrine Tablets)-Fenortho
- Robitussin Peak Cold Nasal Relief (Acetaminophen and Phenylephrine Tablets)-Fentanyl