Fenoldopam Intravenous and Noxivent

• Generic Name: fenoldopam
• Dosage Forms: n.a.
• Other Brand Names: Corlopam

Fenoldopam injection is used for in-hospital, short-term (up to 48 hours) management of severe hypertension (high blood pressure) in adults. It is used when blood pressure is needed to be lowered quickly (including malignant hypertension with deteriorating end-organ function). Fenoldopam is also used in children for in-hospital, short-term (up to 4 hours) reduction of blood pressure.

Fenoldopam is to be given only by or under the supervision of your doctor.

• Generic Name: nitric oxide
• Dosage Forms: gas
• Other Brand Names: Inomax

Used in conjunction with ventilatory support and other appropriate therapy to improve oxygenation and reduce the need for extracorporeal membrane oxygenation (ECMO) in term or near-term (>34 weeks of age) neonates with hypoxic respiratory failure and clinical or ECG evidence of pulmonary hypertension.

Most effective in patients with severe persistent pulmonary hypertension who have minimal underlying parenchymal lung disease (idiopathic persistent pulmonary hypertension).

Least effective in neonates with pulmonary hypoplasia (e.g., congenital diaphragmatic hernia).

Has been used with good results (i.e., decreased the incidence of severe intraventricular hemorrhage and periventricular leukomalacia) in premature neonates (<34 weeks’ gestation) who were undergoing mechanical ventilation for respiratory distress syndrome.