Fenoldopam Intravenous and QC Cold Relief Plus
Determining the interaction of Fenoldopam Intravenous and QC Cold Relief Plus and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:The use of acetaminophen has been associated with a 32% increase in orally-administered fenoldopam plasma concentrations and a 50% increase in the area under the plasma concentration versus time curve for fenoldopam. These data suggest that acetaminophen may significantly increase exposure to fenoldopam and increase its hypotensive effect. Data are available for orally administered fenoldopam only. Since fenoldopam is available as an intravenously administered drug for emergent hypertension, its dose can be rapidly titrated in cases of hypotension.
- Ziemniak JA, Allison N, Boppana VK, Dubb J, Stote R "The effect of acetaminophen on the disposition of fenoldopam: competition for sulfation." Clin Pharmacol Ther 41 (1987): 275-81
- Brogden RN, Markham A "Fenoldopam: a review of its pharmacodynamic and pharmacokinetic properties and intravenous clinical potential in the management of hypertensive urgencies and emergencies." Drugs 54 (1997): 634-50
Generic Name: fenoldopam
Brand name: Corlopam
Synonyms: Fenoldopam
Generic Name: acetaminophen / chlorpheniramine / phenylephrine
Brand name: Alka-Seltzer Plus Cold, Comtrex Severe Cold & Sinus, Contac Cold+Flu Maximum Strength, Dristan Cold Multi Symptom Formula, Robitussin Nighttime Nasal Relief, Tylenol Allergy Multi-Symptom, Tylenol Children's Plus Cold, Tylenol Sinus Congestion Nighttime, Contac Cold/Flu Day & Night, Coricidin D Cold/Flu/Sinus, Dristan Cold, Medicidin-D, Onset Forte, Robitussin Peak Cold Nasal Relief, Super Cold Tabs, Super Strength Sinadrin, Tylenol Sinus Congestion/Pain, Cold Relief Plus, EQL Effervescent Plus Cold, GNP Cold Relief Plus, QC Cold Relief Plus
Synonyms: Acetaminophen, chlorpheniramine, and phenylephrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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