Fenoldopam Intravenous and Tylenol Infants
Determining the interaction of Fenoldopam Intravenous and Tylenol Infants and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:The use of acetaminophen has been associated with a 32% increase in orally-administered fenoldopam plasma concentrations and a 50% increase in the area under the plasma concentration versus time curve for fenoldopam. These data suggest that acetaminophen may significantly increase exposure to fenoldopam and increase its hypotensive effect. Data are available for orally administered fenoldopam only. Since fenoldopam is available as an intravenously administered drug for emergent hypertension, its dose can be rapidly titrated in cases of hypotension.
- Ziemniak JA, Allison N, Boppana VK, Dubb J, Stote R "The effect of acetaminophen on the disposition of fenoldopam: competition for sulfation." Clin Pharmacol Ther 41 (1987): 275-81
- Brogden RN, Markham A "Fenoldopam: a review of its pharmacodynamic and pharmacokinetic properties and intravenous clinical potential in the management of hypertensive urgencies and emergencies." Drugs 54 (1997): 634-50
Generic Name: fenoldopam
Brand name: Corlopam
Synonyms: Fenoldopam
Generic Name: acetaminophen
Brand name: Mapap Infants, Tylenol Infants, Acephen, Feverall, Mapap, Actamin, Anacin AF, Apra, Bromo Seltzer, Children's Tylenol, Elixsure Fever/Pain, Medi-Tabs, Q-Pap, Silapap Childrens, Tactinal, Tempra Quicklets, Tycolene, Tylenol, Vitapap, Children's Silapap, Febrol Solution, Triaminic Fever Reducer, Genapap, Tylenol Junior, Children's Tylenol Meltaways, Junior Tylenol Meltaways, Ofirmev, Tylenol 8 Hour, Tylenol Arthritis Pain, Tylophen
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Fenoldopam Intravenous-Tylenol Junior
- Fenoldopam Intravenous-Tylenol Maximum Strength Flu Nighttime
- Fenoldopam Intravenous-Tylenol NightTime Cold & Flu
- Fenoldopam Intravenous-Tylenol PM
- Fenoldopam Intravenous-Tylenol Severe Allergy
- Fenoldopam Intravenous-Tylenol Sinus Congestion and Pain
- Tylenol Infants-Fenoprofen
- Tylenol Infants-Fenoprofen Calcium
- Tylenol Infants-Fenoprofen Capsules
- Tylenol Infants-Fenortho
- Tylenol Infants-Fentanyl
- Tylenol Infants-Fentanyl Buccal mucosa, Oromucosal