Fentanyl Buccal mucosa, Oromucosal and Otezla

• Generic Name: fentanyl
• Dosage Forms: n.a.
• Other Brand Names: Duragesic, Abstral, Fentora, Subsys, Actiq, Ionsys, Lazanda, Onsolis, Sublimaze

Fentanyl is used to treat severe pain in cancer patients. It is used for breakthrough cancer pain, which are flares of pain that “break through” after a routine pain medicine has been used. Fentanyl belongs to the group of medicines called narcotic analgesics. It is only used in patients who are already taking narcotic analgesics.

Fentanyl acts in the central nervous system (CNS) to relieve pain. Some of its side effects are also caused by actions in the CNS. When a narcotic is used for a long time, it may become habit-forming or cause mental or physical dependence. However, people who have continuous pain should not let the fear of dependence keep them from using narcotics to relieve pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. Withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before the medicine is stopped completely. Talk to your doctor about the benefits of fentanyl and how to prevent withdrawal side effects.

Fentanyl is available only with your doctor's prescription. The Abstral®, Actiq®, Fentora®, Onsolis®, and Subsys® products are only available under a restricted distribution program. You will have to read and sign papers that explain how the medicine is used when you pick up your prescription.

• Generic Name: apremilast
• Dosage Forms: tablet, film coated
• Other Brand Names: Otezla, Otezla Starter Pack

Otezla (apremilast) inhibits an enzyme within your immune system that can affect certain cells and contribute to inflammation in the body.

Otezla is used to treat the symptoms of active psoriatic arthritis in adults.

Otezla can relieve tenderness and swelling in and around the joints, but this medicine is not a cure for psoriatic arthritis.

Otezla is used to treat moderate to severe plaque psoriasis in people who may also receive phototherapy or other treatments for psoriasis.

Otezla is also used to treat adults with oral ulcers associated with Behçet’s Disease.