Fentanyl nasal and Mexiletine Hydrochloride

• Generic Name: fentanyl
• Dosage Forms: n.a.
• Other Brand Names: Duragesic, Abstral, Fentora, Subsys, Actiq, Ionsys, Lazanda, Onsolis, Sublimaze

Fentanyl nasal (for the nose) is an opioid medication used to treat "breakthrough" cancer pain. Fentanyl nasal is not for treating pain that isn't cancer-related, such as pain from surgery, dental work, or migraine headaches.

Fentanyl nasal is given with other non-fentanyl opioid pain medicine that is used around the clock.

Fentanyl nasal may also be used for purposes not listed in this medication guide.

• Generic Name: mexiletine
• Dosage Forms: n.a.
• Other Brand Names: Mexitil

Treatment of documented life-threatening ventricular arrhythmias (e.g., sustained ventricular tachycardia). Use for less severe arrhythmias is notrecommended.

Can reduce ventricular premature contractions (VPCs), paired VPCs, and nonsustained ventricular tachycardia and can suppress the recurrence of ventricular tachycardia and/or fibrillation in patients with ventricular tachycardia and/or fibrillation. Avoid treatment of asymptomatic VPCs.

Has been effective in some patients for the treatment of ventricular arrhythmias unresponsive to other antiarrhythmic agents.

Has been used with equivocal results in the management of painful diabetic neuropathy; pending further accumulation of data from well-designed studies, use only in patients who do not respond to or cannot tolerate more established therapies.