Fetzima Titration Pack and Zykadia

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this interaction is not currently available.ADJUST DOSE: Coadministration with potent inhibitors of CYP450 3A4 may increase the plasma concentrations of levomilnacipran, which is primarily metabolized by the isoenzyme. When coadministered with the potent CYP450 3A4 inhibitor, ketoconazole, levomilnacipran peak plasma concentration (Cmax) and systemic exposure (AUC) increased by approximately 1.4- and 1.6-fold, respectively, compared to administration alone. MANAGEMENT: The dosage of levomilnacipran should not exceed 80 mg once daily when used with potent CYP450 3A4 inhibitors. References "Product Information. Fetzima (levomilnacipran)." Forest Pharmaceuticals, St. Louis, MO.

ADJUST DOSE: Coadministration with potent inhibitors of CYP450 3A4 may increase the plasma concentrations of levomilnacipran, which is primarily metabolized by the isoenzyme. When coadministered with the potent CYP450 3A4 inhibitor, ketoconazole, levomilnacipran peak plasma concentration (Cmax) and systemic exposure (AUC) increased by approximately 1.4- and 1.6-fold, respectively, compared to administration alone.

MANAGEMENT: The dosage of levomilnacipran should not exceed 80 mg once daily when used with potent CYP450 3A4 inhibitors.

Fetzima Titration Pack

Generic Name: levomilnacipran

Brand name: Fetzima

Synonyms: Levomilnacipran

What is Fetzima Titration Pack?

Zykadia

Generic Name: ceritinib

Brand name: Zykadia

Synonyms: n.a.

What is Zykadia?