First - Lansoprazole and Unasyn
Determining the interaction of First - Lansoprazole and Unasyn and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using ampicillin together with lansoprazole. By reducing stomach acid, lansoprazole can decrease the absorption and blood levels of ampicillin and make the medication less effective against infections. Your doctor or pharmacist may be able to offer suggestions on safer alternatives if you require treatment for stomach acid or ulcer while you are being treated with ampicillin. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Because lansoprazole increases gastric pH, it theoretically could decrease absorption of drugs like ampicillin which require an acidic environment.
MANAGEMENT: If lansoprazole therapy is required, consideration should be given to alternative antimicrobial agents.
- "Product Information. Prevacid (lansoprazole)." TAP Pharmaceuticals Inc, Deerfield, IL.
- "Product Information. Kapidex (dexlansoprazole)." Takeda Pharmaceuticals America, Lincolnshire, IL.
Generic Name: lansoprazole
Brand name: FIRST Lansoprazole, Prevacid, Prevacid OTC, Prevacid SoluTab
Synonyms: Lansoprazole
Generic Name: ampicillin / sulbactam
Brand name: Unasyn, Unasyn ADD-Vantage
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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