FIRST-Progesterone VGS 200 and Perflutren protein type a microsphere Intravenous

• Generic Name: progesterone
• Dosage Forms: n.a.
• Other Brand Names: First Progesterone MC10, Menopause Formula Progesterone, Prometrium, Crinone, Endometrin, FIRST-Progesterone VGS 200, Prochieve

Progesterone is a female hormone important for ovulation and menstruation. Progesterone causes changes in the lining of your uterus, making it easier for a fertilized egg to attach to the uterus at the beginning of pregnancy. Progesterone then helps your body maintain the pregnancy.

FIRST-Progesterone VGS 200 (for use in the vagina) is used to cause menstrual periods in women who have not yet reached menopause but are not having periods due to a lack of progesterone in the body.

FIRST-Progesterone VGS 200 is also used in fertility treatment as part of Assisted Reproductive Technology (ART) for women unable to get pregnant due to a lack of natural progesterone in the body.

FIRST-Progesterone VGS 200 is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.

FIRST-Progesterone VGS 200 may also be used for purposes not listed in this medication guide.

• Generic Name: perflutren
• Dosage Forms: n.a.
• Other Brand Names: Definity, Optison

Perflutren protein type A microsphere injection is used during an echocardiogram to help diagnose or find problems in the heart.

Perflutren protein type A microsphere is an ultrasound contrast agent. Ultrasound contrast agents are used to help provide a clear picture during ultrasound. Ultrasound is a special kind of diagnostic procedure. It uses high-frequency sound waves to create images or “pictures” of certain areas inside the body. The sound waves produced by the ultrasound equipment can be reflected (bounced off) by different parts of the body, such as, the heart. As the sound waves return they are electronically converted into images on a television screen. Unlike x-rays, ultrasound does not involve ionizing radiation. The albumin microspheres sonicated preparation contains very small gas-filled albumin microspheres that reflect the sound waves and help create a better picture.

Perflutren protein type a microsphere is to be given only by or under the direct supervision of a doctor with specialized training in ultrasound procedures.