Flecainide Acetate and Sodium Citrate and Citric Acid
Determining the interaction of Flecainide Acetate and Sodium Citrate and Citric Acid and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Agents that alkalinize the urine decrease the renal elimination of flecainide. The result may be increased plasma flecainide levels and increased effectiveness. The patient should be monitored for flecainide toxicity, and plasma flecainide levels should be checked when appropriate. Also, flecainide effectiveness may be decreased when an agent that alkalinizes the urine is discontinued.
- Hertrampf R, Gundert-Remy U, Beckmann J, et al "Elimination of flecainide as a function of urinary flow rate and pH." Eur J Clin Pharmacol 41 (1991): 61-3
Generic Name: flecainide
Brand name: Tambocor
Synonyms: Flecainide
Generic Name: citric acid / sodium citrate
Brand name: Bicitra, Cytra-2, Liqui-Dual Citra, Oracit, Shohl's Solution, Virtrate-2
Synonyms: Citric acid and sodium citrate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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- Sodium Citrate and Citric Acid-Flector
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- Sodium Citrate and Citric Acid-Fleet Babylax