Flibanserin and Topiragen
Determining the interaction of Flibanserin and Topiragen and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using flibanserin together with topiramate may increase side effects such as dizziness, drowsiness, fatigue, and difficulty concentrating. You should avoid the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery for at least 6 hours after taking flibanserin and until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The central nervous system (CNS) effects of flibanserin such as somnolence and fatigue may be potentiated by concomitant use of other agents with CNS depressant effects. In five 24-week clinical trials, the incidence of somnolence, sedation, or fatigue was 21% and 8% in patients treated with flibanserin 100 mg once daily at bedtime and placebo, respectively. The risk of CNS depression is increased if flibanserin is taken during waking hours or with alcohol or other CNS depressants.
MANAGEMENT: Patients receiving flibanserin with other agents that can cause CNS depression should be apprised of the potential for increased adverse effects such as drowsiness, dizziness, lightheadedness, and fatigue. Patients should not drive, operate machinery, or engage in hazardous activities requiring mental alertness and motor coordination for at least 6 hours after taking flibanserin and until they know how the medication affects them.
- "Product Information. Addyi (flibanserin)." Sprout Pharmaceuticals, Raleigh, NC.
Generic Name: topiramate
Brand name: Qudexy XR Sprinkle, Topamax, Topamax Sprinkle, Trokendi XR, Qudexy XR, Topiragen
Synonyms: Topiragen (Oral)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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