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Fluconazole Oral Suspension and Meloxicam

Determining the interaction of Fluconazole Oral Suspension and Meloxicam and the possibility of their joint administration.

Check result:
Fluconazole Oral Suspension <> Meloxicam
Relevance: 08.11.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Fluconazole may increase the blood levels and effects of meloxicam. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Coadministration with inhibitors of CYP450 2C9 may increase the plasma concentration of meloxicam, which is a substrate of the isoenzyme.

MANAGEMENT: The potential for an interaction should be considered during concomitant use. It is recommended to monitor patients for NSAID-related side effects and toxicity. Dose adjustment of meloxicam may be warranted.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • Cerner Multum, Inc. "Australian Product Information." O 0
Fluconazole Oral Suspension

Generic Name: fluconazole

Brand name: Diflucan

Synonyms: Fluconazole

Meloxicam

Generic Name: meloxicam

Brand name: Mobic, Vivlodex, Meloxicam Comfort Pac [DSC], Qmiiz ODT

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle