Fluocinolone, hydroquinone, and tretinoin Topical application and Larotrectinib

• Generic Name: fluocinolone / hydroquinone / tretinoin topical
• Dosage Forms: n.a.
• Other Brand Names: Tri-Luma

Fluocinolone, hydroquinone, and tretinoin topical is a combination of medicines used to treat moderate to severe melasma (skin discoloration) of the face. Melasma usually happens with hormone changes in women.

Fluocinolone is a corticosteroid (steroid medicine), hydroquinone is a bleaching agent, and tretinoin is a retinoid (related to vitamin A).

Fluocinolone, hydroquinone, and tretinoin is available only with your doctor's prescription.

• Generic Name: larotrectinib
• Dosage Forms: n.a.
• Other Brand Names: Vitrakvi

Larotrectinib is used to treat certain tumors that are caused by an abnormal "NTRK" gene. Larotrectinib is used when the cancer has spread to other parts of the body or cannot be removed with surgery or other cancer treatments.

Larotrectinib is sometimes given after other cancer treatments did not work or have stopped working.

Larotrectinib was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to larotrectinib, but further studies are needed.

Larotrectinib may also be used for purposes not listed in this medication guide.