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Fluoxetine Capsules and Tablets (PMDD) and Seconal Sodium

Determining the interaction of Fluoxetine Capsules and Tablets (PMDD) and Seconal Sodium and the possibility of their joint administration.

Check result:

Fluoxetine Capsules and Tablets (PMDD) <> Seconal Sodium

Relevance: 03.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Animal studies have suggested that fluoxetine may potentiate the effects of barbiturates. The mechanism may be related to inhibition of barbiturate metabolism. This interaction has not been reported in humans. Until further information is available concerning this interaction, caution is recommended if fluoxetine and a barbiturate must be used together. Monitoring for prolonged or excessive CNS-depressant effects is recommended.

References

Ciraulo DA, Shader RI "Fluoxetine drug-drug interactions. II." J Clin Psychopharmacol 10 (1990): 213-7
Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):

Fluoxetine Capsules and Tablets (PMDD)

Generic Name: fluoxetine

Brand name: Prozac, Prozac Weekly, PROzac Pulvules, Sarafem, Rapiflux, Selfemra

Synonyms: Fluoxetine, FLUoxetine

What is Fluoxetine Capsules and Tablets (PMDD)?

Seconal Sodium

Generic Name: secobarbital

Brand name: Seconal Sodium, Seconal

Synonyms: n.a.

What is Seconal Sodium?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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