Fluoxetine Solution and Phenobarbital
Determining the interaction of Fluoxetine Solution and Phenobarbital and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Animal studies have suggested that fluoxetine may potentiate the effects of barbiturates. The mechanism may be related to inhibition of barbiturate metabolism. This interaction has not been reported in humans. Until further information is available concerning this interaction, caution is recommended if fluoxetine and a barbiturate must be used together. Monitoring for prolonged or excessive CNS-depressant effects is recommended.
- Ciraulo DA, Shader RI "Fluoxetine drug-drug interactions. II." J Clin Psychopharmacol 10 (1990): 213-7
- Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):
Generic Name: fluoxetine
Brand name: Prozac, Prozac Weekly, PROzac Pulvules, Sarafem, Rapiflux, Selfemra
Synonyms: Fluoxetine, FLUoxetine
Generic Name: phenobarbital
Brand name: Solfoton, Luminal
Synonyms: PHENobarbital
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Fluoxetine Solution-Phenobarbital Elixir
- Fluoxetine Solution-Phenobarbital Injection
- Fluoxetine Solution-Phenobarbital Oral Solution
- Fluoxetine Solution-Phenobarbital Sodium
- Fluoxetine Solution-Phenobarbital Sodium Injection
- Fluoxetine Solution-Phenobarbital Tablets
- Phenobarbital-Fluoxiv Cream
- Phenobarbital-Fluoxymesterone
- Phenobarbital-Fluphenazine
- Phenobarbital-Fluphenazine decanoate
- Phenobarbital-Fluphenazine Decanoate Injection
- Phenobarbital-Fluphenazine Elixir