Fluphenazine decanoate and Lorlatinib

• Generic Name: fluphenazine
• Dosage Forms: n.a.
• Other Brand Names: Permitil, Prolixin, Prolixin Decanoate, Prolixin Enanthate

Symptomatic management of psychotic disorders (i.e., schizophrenia).

The long-acting decanoate ester is used mainly for maintenance therapy in patients with chronic schizophrenic disorder who cannot be relied on to take oral antipsychotic drugs; do not use for acute management of severely agitated patients.

Efficacy not established for management of behavioral complications in mental retardation.

• Generic Name: lorlatinib
• Dosage Forms: n.a.
• Other Brand Names: Lorbrena

Lorlatinib is used to treat a certain type of non-small cell lung cancer that has spread to other parts of the body.

Lorlatinib is used only if your cancer has a specific genetic marker (an abnormal "ALK" gene). Your doctor will test you for this gene.

Lorlatinib is given after other cancer treatments did not work or have stopped working.

Lorlatinib was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to lorlatinib, but further studies are needed.

Lorlatinib may also be used for purposes not listed in this medication guide.