Fluphenazine hydrochloride and Nexiclon XR Suspension
Determining the interaction of Fluphenazine hydrochloride and Nexiclon XR Suspension and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using cloNIDine together with fluPHENAZine may have additive low blood pressure effects and cause delirium. Contact your doctor if you experience dizziness, weakness, faint, confusion or disorientation. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant administration of clonidine and fluphenazine may have additive hypotensive effects and cause delirium. The mechanism is unknown.
MANAGEMENT: Patients should be monitored for adverse cardiovascular and CNS effects especially when initiating therapy, and advised to notify their physician if they experience dizziness, weakness, syncope, orthostasis, confusion or disorientation.
- Markowitz JS, Wells BG, Carson WH "Interactions between antipsychotic and antihypertensive drugs." Ann Pharmacother 29 (1995): 603-9
- Allen RM, Flemenbaum A "Delirium associated with combined fluphenazine-clonidine therapy." J Clin Psychiatry 40 (1979): 236-7
Generic Name: fluphenazine
Brand name: Permitil, Prolixin, Prolixin Decanoate, Prolixin Enanthate
Synonyms: Fluphenazine, FluPHENAZine
Generic Name: clonidine
Brand name: Catapres, Catapres-TTS, Duraclon, Kapvay, Catapres-TTS-1, Catapres-TTS-2, Catapres-TTS-3
Synonyms: Nexiclon XR (Oral), Nexiclon XR
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Fluphenazine hydrochloride-Nexium
- Fluphenazine hydrochloride-Nexium (Esomeprazole Delayed-Release Capsules)
- Fluphenazine hydrochloride-Nexium (Esomeprazole Powder for Suspension)
- Fluphenazine hydrochloride-Nexium 24HR (Esomeprazole Delayed-Release Capsules)
- Fluphenazine hydrochloride-NexIUM 24HR (Esomeprazole Delayed-Release Tablets)
- Fluphenazine hydrochloride-Nexium Capsules
- Nexiclon XR Suspension-Fluphenazine Hydrochloride Injection
- Nexiclon XR Suspension-Fluphenazine Injection
- Nexiclon XR Suspension-Fluphenazine Oral Concentrate
- Nexiclon XR Suspension-Fluphenazine Oral Solution
- Nexiclon XR Suspension-Fluphenazine Tablets
- Nexiclon XR Suspension-Flurandrenolide