Flurandrenolide and Meclofenamate Sodium

• Generic Name: flurandrenolide topical
• Dosage Forms: n.a.
• Other Brand Names: Cordran, Cordran SP, Cordran Tape, Nolix

Relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Generally most effective in acute or chronic dermatoses (e.g., seborrheic or atopic dermatitis, localized neurodermatitis, anogenital pruritus, psoriasis, late phase of allergic contact dermatitis, inflammatory phase of xerosis).

Topical therapy generally preferred over systemic therapy; fewer associated adverse systemic effects.

Topical therapy generally only controls manifestations of dermatoses; eliminate cause if possible.

Topical efficacy may be increased by using a higher concentration or occlusive dressing therapy. (See Administration with Occlusive Dressing under Dosage and Administration.)

Response may vary from one topical corticosteroid preparation to another.

Anti-inflammatory activity may vary considerably depending on the vehicle, drug concentration, site of application, disease, and individual patient.

Flurandrenolide 0.05% ointment is considered to have high-range potency.

Flurandrenolide 0.05% cream is considered to have medium-range potency.

• Generic Name: meclofenamate
• Dosage Forms: n.a.
• Other Brand Names:

  Meclomen

Consider potential benefits and risks of meclofenamate sodium therapy as well as alternative therapies before initiating therapy with the drug. Use lowest effective dosage and shortest duration of therapy consistent with the patient’s treatment goals.

Symptomatic treatment of acute and chronic osteoarthritis and rheumatoid arthritis.

Has been used with some success in a limited number of adults with ankylosing spondylitis or acute gouty arthritis.

Has been used in a limited number of patients with psoriatic arthritis.

Relief of mild to moderate pain in adults.

Treatment of primary dysmenorrhea.

Treatment of idiopathic menorrhagia. Use only for heavy menstrual flow that is idiopathic (i.e., no underlying pathophysiologic cause can be identified); do not use for the management of spotting or bleeding that occurs between menstrual cycles.

Use for primary dysmenorrhea or idiopathic menorrhagia only when the potential benefits justify the possible risks.