Fluticasone (Oral Inhalation) and Viramune (Nevirapine Oral Suspension)
Determining the interaction of Fluticasone (Oral Inhalation) and Viramune (Nevirapine Oral Suspension) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.MONITOR: Coadministration with nevirapine may decrease the plasma concentrations and therapeutic efficacy of drugs that are substrates of CYP450 3A4. The proposed mechanism is increased clearance due to nevirapine-mediated induction of CYP450 3A4. MANAGEMENT: Caution is advised if nevirapine is used concomitantly with drugs that are CYP450 3A4 substrates. Dosage adjustments as well as clinical and laboratory monitoring of coadministered drugs should be considered whenever nevirapine is added to or withdrawn from therapy. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 "Product Information. Viramune XR (nevirapine)." Boehringer Ingelheim, Ridgefield, CT. Cerner Multum, Inc. "Australian Product Information." O 0 "Product Information. Viramune (nevirapine)." Boehringer-Ingelheim, Ridgefield, CT. View all 4 references
Professional:MONITOR: Coadministration with nevirapine may decrease the plasma concentrations and therapeutic efficacy of drugs that are substrates of CYP450 3A4. The proposed mechanism is increased clearance due to nevirapine-mediated induction of CYP450 3A4.
MANAGEMENT: Caution is advised if nevirapine is used concomitantly with drugs that are CYP450 3A4 substrates. Dosage adjustments as well as clinical and laboratory monitoring of coadministered drugs should be considered whenever nevirapine is added to or withdrawn from therapy.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Viramune XR (nevirapine)." Boehringer Ingelheim, Ridgefield, CT.
- Cerner Multum, Inc. "Australian Product Information." O 0
- "Product Information. Viramune (nevirapine)." Boehringer-Ingelheim, Ridgefield, CT.
Generic Name: fluticasone
Brand name: ArmonAir RespiClick 113, Arnuity Ellipta, Flovent Diskus, Flovent HFA, Flovent, Flovent Rotadisk, ArmonAir RespiClick 55, ArmonAir RespiClick 232
Synonyms: Fluticasone inhalation
Generic Name: nevirapine
Brand name: Viramune, Viramune XR
Synonyms: Viramune
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Fluticasone (Oral Inhalation)-Viramune (Nevirapine Tablets)
- Fluticasone (Oral Inhalation)-Viramune O/S
- Fluticasone (Oral Inhalation)-Viramune Suspension
- Fluticasone (Oral Inhalation)-Viramune XR
- Fluticasone (Oral Inhalation)-Virasal
- Fluticasone (Oral Inhalation)-Virasal Topical
- Viramune (Nevirapine Oral Suspension)-Fluticasone and salmeterol
- Viramune (Nevirapine Oral Suspension)-Fluticasone and Salmeterol Diskus
- Viramune (Nevirapine Oral Suspension)-Fluticasone and Salmeterol inhalation
- Viramune (Nevirapine Oral Suspension)-Fluticasone and Salmeterol Inhalation Powder
- Viramune (Nevirapine Oral Suspension)-Fluticasone and salmeterol Inhalation, oral/nebulization
- Viramune (Nevirapine Oral Suspension)-Fluticasone and Salmeterol Inhaler