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Fluvastatin and Lanoxin (Digoxin Injection)

Determining the interaction of Fluvastatin and Lanoxin (Digoxin Injection) and the possibility of their joint administration.

Check result:

Fluvastatin <> Lanoxin (Digoxin Injection)

Relevance: 16.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Limited data suggest that fluvastatin may slightly increase the plasma clearance of digoxin by an unknown mechanism. The clinical significance of this interaction is unknown. Digoxin serum concentrations and clinical response should be monitored during concomitant therapy. Patients should be advised to notify their physician if they experience nausea, anorexia, visual disturbances, slow pulse, or irregular heartbeats.

References

"Product Information. Lescol (fluvastatin)." Novartis Pharmaceuticals, East Hanover, NJ.
Deslypere JP "Clinical implications of the biopharmaceutical properties of fluvastatin." Am J Cardiol 73 (1994): d12-7
Garnett WR, Venitz J, Wilkens RC, Dimenna G "Pharmacokinetic effects of fluvastatin in patients chronically receiving digoxin." Am J Med 96 (1994): s84-6

Fluvastatin

Generic Name: fluvastatin

Brand name: Lescol, Lescol XL

Synonyms: n.a.

What is Fluvastatin?

Lanoxin (Digoxin Injection)

Generic Name: digoxin

Brand name: Lanoxin, Digitek, Digox, Lanoxicaps, Cardoxin

Synonyms: Lanoxin

What is Lanoxin (Digoxin Injection)?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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