Forane and Isoniazid Solution

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using isoniazid together with isoflurane can be harmful to the kidneys. Symptoms of kidney damage include swelling, weight gain, feeling short of breath, drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting, pain in your lower back, and urinating more or less than usual or not at all. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or special tests to safely use these medications together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Nephrotoxic concentrations of inorganic fluoride may occur in patients receiving enflurane anesthesia while on isoniazid therapy. A similar effect has been noted for isoflurane, in vitro. The isoniazid metabolite, hydrazine, facilitates defluorination of the anesthetic . Hydrazine concentrations are highest in fast acetylators of isoniazid.

MANAGEMENT: Renal function should be monitored postsurgically, especially in fast acetylators of isoniazid.

Forane

Generic Name: isoflurane

Brand name: Forane, Terrell

Synonyms: n.a.

What is Forane?

Isoniazid Solution

Generic Name: isoniazid

Brand name: Nydrazid

Synonyms: Isoniazid

What is Isoniazid Solution?