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Fosamprenavir and Paroxetine Oral Suspension

Determining the interaction of Fosamprenavir and Paroxetine Oral Suspension and the possibility of their joint administration.

Check result:
Fosamprenavir <> Paroxetine Oral Suspension
Relevance: 21.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using fosamprenavir together with PARoxetine can decrease the effects of PARoxetine. Contact your doctor if your condition worsens. You may need a dose adjustment or special tests if your use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Coadministration with fosamprenavir/ritonavir may significantly decrease the plasma concentrations of paroxetine. The mechanism of interaction has not been described.

MANAGEMENT: Pharmacologic response to paroxetine should be monitored more closely whenever fosamprenavir/ritonavir is added to or withdrawn from stabilized therapy, and the paroxetine dosage adjusted as necessary.

References
  • "Product Information. Paxil (paroxetine)." GlaxoSmithKline, Research Triangle Park, NC.
Fosamprenavir

Generic Name: fosamprenavir

Brand name: Lexiva, Telzir

Synonyms: n.a.

Paroxetine Oral Suspension

Generic Name: paroxetine

Brand name: Brisdelle, Paxil, Paxil CR, Pexeva

Synonyms: Paroxetine, PARoxetine

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle