Fosnetupitant and Palonosetron and Tegsedi

• Generic Name: fosnetupitant / palonosetron
• Dosage Forms: n.a.
• Other Brand Names: Akynzeo for injection

• It is used to prevent upset stomach and throwing up from chemo.

• Generic Name: inotersen
• Dosage Forms: injection, solution
• Other Brand Names: Tegsedi

Tegsedi (inotersen) works by decreasing a protein called transthyretin (TTR, made primarily in the liver). Hereditary transthyretin-mediated amyloidosis (hATTR) is a rare condition in which abnormal deposits of TTR protein build up in many parts of the body, interfering with normal function.

Tegsedi injection is used to treat polyneuropathy (damage of multiple nerves throughout the body) in adults with hATTR. This medicine can help reduce symptoms such as pain, numbness, tingling, abnormal heartbeats, diarrhea, constipation, weakness, and problems with movement in your arms or legs.

Tegsedi is available only from a certified pharmacy under a special program.