Fosnetupitant/palonosetron Intravenous and Oxymetazoline Hydrochloride

• Generic Name: fosnetupitant / palonosetron
• Dosage Forms: n.a.
• Other Brand Names: Akynzeo for injection

Fosnetupitant and palonosetron combination injection is used together with dexamethasone to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy). Palonosetron and fosnetupitant work by blocking the signals to the brain that cause nausea and vomiting.

Fosnetupitant/palonosetron is to be given only by or under the direct supervision of your doctor.

• Generic Name: oxymetazoline ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Visine LR, Visine Long Lasting, Ocuclear

Self-medication for temporary relief of nasal congestion associated with the common cold, hay fever, or other upper respiratory allergies.

As effective as other topical vasoconstrictors.

Labeled and has been used for self-medication for temporary relief of nasal congestion associated with sinusitis; however, efficacy data are lacking and/or controversial. In October 2005, FDA issued final rule to remove this indication from labeling of OTC nasal decongestants. Compliance date for preparations with annual sales <$25,000 is October 11, 2007; compliance date for all other preparations is April 11, 2007.

Self-medication for temporary relief of ocular redness due to minor irritation.

Has been used for self-medication for symptomatic prevention of otitic barotrauma (aerotitis [barotitis] media); however, no more effective than placebo.