Fosphenytoin Injection and Mivacron

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using fosphenytoin together with mivacurium may alter the effects of mivacurium and cause your condition to change. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Case reports have suggested that long-term phenytoin administration may decrease the effectiveness of neuromuscular blocker and increase the dosage requirements. One of the proposed mechanisms is hepatic enzyme induction by phenytoin. Conversely, acute phenytoin administration may increase neuromuscular blocking effects by an unknown mechanism. Other hydantoins may interact with other non-depolarizing neuromuscular blockers in a similar fashion.

MANAGEMENT: Close observation for evidence of altered effects of neuromuscular blocking agents is indicated if these drugs must be used together.

Fosphenytoin Injection

Generic Name: fosphenytoin

Brand name: Cerebyx

Synonyms: Fosphenytoin

What is Fosphenytoin Injection?

Mivacron

Generic Name: mivacurium

Brand name: Mivacron

Synonyms: n.a.

What is Mivacron?