Frovatriptan Succinate and Norgestrel, ethinyl estradiol, and ferrous fumarate
Determining the interaction of Frovatriptan Succinate and Norgestrel, ethinyl estradiol, and ferrous fumarate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:The concurrent use of oral contraceptives may increase the plasma concentrations of frovatriptan. According to the manufacturer, retrospective analysis of pharmacokinetic data from females across trials indicated that the mean peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) of frovatriptan are 30% higher in oral contraceptive users compared to non-users. The mechanism of interaction has not been established, and it is not known if hormonal contraceptives delivered by other routes (intravaginal, transdermal) may similarly affect the pharmacokinetics of frovatriptan. Regardless, this interaction is unlikely to be of clinical significance.
- "Product Information. Frova (frovatriptan)." Endo Laboratories LLC, Chadds Ford, PA.
Generic Name: frovatriptan
Brand name: Frova
Synonyms: Frovatriptan
Generic Name: ethinyl estradiol / norgestrel
Brand name: Cryselle 28, Low-Ogestrel, Ogestrel-28, Lo/Ovral-21, Lo/Ovral-28, Ovral, Ovral-28, Low-Ogestrel-21, Ovral-21, Elinest, Cryselle-28, Ogestrel
Synonyms: Ethinyl estradiol and norgestrel, Norgestrel and Ethinyl Estradiol
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Frovatriptan Succinate-Norinyl 1+35 birth control
- Frovatriptan Succinate-Norinyl 1+50 (28)
- Frovatriptan Succinate-Noritate
- Frovatriptan Succinate-Noritate Topical
- Frovatriptan Succinate-Norlyda
- Frovatriptan Succinate-Norlyroc
- Norgestrel, ethinyl estradiol, and ferrous fumarate-Frovatriptan Succinate Tablets
- Norgestrel, ethinyl estradiol, and ferrous fumarate-FUDR
- Norgestrel, ethinyl estradiol, and ferrous fumarate-Ful-Glo
- Norgestrel, ethinyl estradiol, and ferrous fumarate-Fulphila
- Norgestrel, ethinyl estradiol, and ferrous fumarate-Fulphila Injection
- Norgestrel, ethinyl estradiol, and ferrous fumarate-Fulphila Subcutaneous